recent applications of dna vaccines in cancer therapy

نویسندگان

ali akbar poursadegh zonouzi department of genetics and medical biotechnology, faculty of medicine, hormozgan university of medical sciences, bandar abbas, iran

ahmad poursadegh zonouzi biotechnology research center, tabriz university of medical sciences, tabriz, iran

morteza abkar department of applied cell sciences, kashan university of medical sciences, kashan, iran

چکیده

dna vaccination has been developed as a noteworthy immunotherapeutic approach for the battle against many serious challenges to human and animal safety, including infectious illnesses, autoimmunity, allergy and cancer. clinical trials prepare chances to examine whether dna vaccines can fulfill their final aim of demonstrating efficiency in treating humans. today, anticancer dna vaccines are quickly moving from the bench to the bedside, and several therapeutic and prophylactic preparations have already been licensed by fda for application in humans. in this review, we describe an insightful and unbiased summary of outcomes from a set of current clinical trials on dna vaccines against diverse cancers.

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